There have been mixed results on the health effects of reducing the number of calories we intake. Multiple studies have shown that long-term calorie reduction can reduce metabolic function and slow the cellular aging process, but they have been on rats and not humans. A study which was published in the journal The Lancet found that people who reduced their calorie intake by 12% had lower blood pressure and cholesterol and increased insulin sensitivity. However it was a small study of 238 people so it must be followed up on (AARP Magazine, April/May 2022). What we do know is that diets low in fat and high in fiber and vegetables such as The Mediterranean Diet have shown many health benefits. And if you are obese, there are most certainly health benefits with losing weight.