650K Americans will die from heart disease this year, and more than half of them—roughly 490K—won’t have seen it coming. That’s because about 60% of people who have a heart attack have no prior symptoms. Dr. James Min, a cardiologist, is hoping to change these statistics at his start-up Cleerly, which will use machine learning to help doctors personalize heart disease treatment plans before patients end up in the ER. He calls his company’s approach â€precision prevention.â€Â Dr Min says that the market opportunity is massive, with more than 100 million Americans at risk of having a heart attack.